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本片根据石之森章太郎的经典漫画原作改编。
Karl Hochman, a technician in a computer shop, is also "The Address-Book Killer", who obtains the names of his victims from stolen address-books. Terry Munroe and her son Josh come into the store to price software, and a salesman uses Terry's address-book to demonstrate a hand-held scanner. Karl obtains the file, and while driving to Terry's house that night in a heavy electrical storm, his car runs off the road and lands upside down in a cemetery. While Karl is undergoing a CAT scan at the hospital, a surge of lightning courses through the building, and Karl's mind is transformed into electrical energy. Karl uses the electrical grid and computer networks to continue his killing-spree.
校队篮球运动员马特（Brian Lloyd 饰）等人经历了一场暴力的校际篮球比赛，对方粗野的主场把马特与队友乔伊、布莱恩送进了当地医院。乔伊小妹切丽暗恋马特，无奈马特的拉拉队长女友不给机会。另一方面，这所医院收治的一名女性病人被外星生物寄生，寄生生物通过控制宿主陆续感染控制了护士、医生以及病人。女性感染后被充作寄生生物的诱饵，而男性则化为无自我意识的养料。
马特等人发现了医院的异样，但为时已晚，感染者在医院中横行，乔伊也因受伤开始转化。走投无路的年轻人们决意对抗外星生物，他们摧毁了地下室中的外星培养缸，切丽更发现了这种嗜甜生物的致命弱点……
